Browsing by Subject
Showing results 1 to 20 of 211
next >
- Baba Arago 1
- Background. Decentralization of antiretroviral therapy (ART) services is a key strategy to achieving universal access to treatment for people living with HIV/AIDS. Our objective was to assess clinical and laboratory outcomes within a decentralized program in Nigeria. Methods. Using a tiered hub-and-spoke model to decentralize services, a tertiary hospital scaled down services to 13 secondary-level hospitals using national and program guidelines. We obtained sociodemographic, clinical, and immunovirologic data on previously antiretroviral drug naΒ¨Δ±ve patients aged β₯15 years that received HAART for at least 6 months and compared treatment outcomes between the prime and satellite sites. Results. Out of 7,747 patients, 3729 (48.1%) were enrolled at the satellites while on HAART, prime site patients achieved better immune reconstitution based on CD4+ cell counts at 12 (π < 0.001)and24 weeks (π < 0.001)withsimilarresponsesat48weeks(π = 0.11) and higher rates of viral suppression (<400c/mL)at12(π < 0.001) and 48 weeks (π = 0.03), but similar responses at 24 weeks (π = 0.21). Mortality was 2.3% versus 5.0% (π < 0.001)atprimeand satellite sites, while transfer rate was 8.7% versus 5.5% (π = 0.001)atprimeandsatellites.Conclusion. ART decentralization is feasible in resource-limited settings, but efforts have to be intensified to maintain good quality of care 1
- Bacteri 1
- Bacteria 3
- bacteria 1
- Bacteria; Uke River; fecal coliform; water 1
- Bacterial contaminant 1
- Bacterial contamination 1
- bacterial, vaginosis, women delivery, pregnancy outcomes 1
- bactericidal 1
- Bacteriophage 1
- Bacteriuria 1
- Balance of payment 1
- Balanite aegyptiaca 1
- Balanites aegyptiaca 1
- Ballooned hepatocyte 1
- Ballooning degenerations 1
- Banana 1
- Banana peel 1
- Banditry 2