Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/630
Title: Hypoglycaemic Effect of Gongronema Latifolium in Alloxan-Diabetic Rabbits
Authors: Akande, T.
Balogun, S. T.
Egbuzu, P.
BUILDERS, Modupe I.
Ogundeko, T. O.
Ramyil, M. S. C
Keywords: metformin
Orcytolagus cuniculus
Alloxan-induced diabetes
Antihyperglcaemic effect
blood glucose
diabetes mellitus
Gongronema latifolium
Issue Date: Jun-2020
Publisher: BINGHAM JOURNAL OF MEDICINE (BJM) Vol. 2 No. 1
Abstract: BACKGROUND: Gongronema latifolium is an edible and a medicinal plant. The plant has been reported to possess several useful effects in man. OBJECTIVE: To determine the blood glucose lowering effect of Gongronema latifolium in diabetes mellitus. METHODS: Diabetes mellitus was induced in male rabbits by intravenous injection of alloxan. The alloxan induced diabetic rats were then given a Gongronema latifolium extract or metformin. Blood glucose was subsequently monitored for 24 hours. RESULTS: The Glatifolium extracts showed a significant hypoglycaemic effect on both normal and diabetic rabbits. Blood glucose levels were either as low or lower after the administration of G latifolium than metformin. CONCLUSION: The results of these study confirm that G latifolium extract lowers blood glucose. This suggests that it has a possible use as a dietary adjunct in the management of diabetes mellitus. BJM 2020; 2(1): 19-21.
URI: http://localhost:8080/xmlui/handle/123456789/630
ISSN: 2705-263X
Appears in Collections:Research Articles

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