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Title: | Hypoglycaemic Effect of Gongronema Latifolium in Alloxan-Diabetic Rabbits |
Authors: | Akande, T. Balogun, S. T. Egbuzu, P. BUILDERS, Modupe I. Ogundeko, T. O. Ramyil, M. S. C |
Keywords: | metformin Orcytolagus cuniculus Alloxan-induced diabetes Antihyperglcaemic effect blood glucose diabetes mellitus Gongronema latifolium |
Issue Date: | Jun-2020 |
Publisher: | BINGHAM JOURNAL OF MEDICINE (BJM) Vol. 2 No. 1 |
Abstract: | BACKGROUND: Gongronema latifolium is an edible and a medicinal plant. The plant has been reported to possess several useful effects in man. OBJECTIVE: To determine the blood glucose lowering effect of Gongronema latifolium in diabetes mellitus. METHODS: Diabetes mellitus was induced in male rabbits by intravenous injection of alloxan. The alloxan induced diabetic rats were then given a Gongronema latifolium extract or metformin. Blood glucose was subsequently monitored for 24 hours. RESULTS: The Glatifolium extracts showed a significant hypoglycaemic effect on both normal and diabetic rabbits. Blood glucose levels were either as low or lower after the administration of G latifolium than metformin. CONCLUSION: The results of these study confirm that G latifolium extract lowers blood glucose. This suggests that it has a possible use as a dietary adjunct in the management of diabetes mellitus. BJM 2020; 2(1): 19-21. |
URI: | http://localhost:8080/xmlui/handle/123456789/630 |
ISSN: | 2705-263X |
Appears in Collections: | Research Articles |
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