Abstract:
Protective effects of phytochemicals offer notable prospects in exploring new
therapeutics. Herbs are effective treatments of Peptic ulcer diseases than synthetic drugs. Most
synthetic drugs cause adverse effects including impotence and hematopoietic disorders on
chronic usage. Current treatments mainly targets potentiation defensive system of
gastrointestinal tract with lowering acid secretion. Cadaba farinosa is a flowering plant in the
Capparidecae family with high ethno-medicinal value, referred as ‘mucosae plant medicine’.
Traditionally, it’s used for treatments of diarrhoea, dysentery and intestinal helminthes. This
study investigated cytoprotective effects of oral administration of aqueous leaf extracts. Sixteen
adult Wistar rats were divided into four groups of four rats. Group 1 is control. Extract
administered to groups (2, 3 and 4) at 100, 200 and 300 mg/kg, showed increased goblet cells
secreting mucus; a major lining epithelia vulnerable to cellular compartment. Hence,
phytochemicals offers notable prospect for exploring new therapeutics
