Abstract:
Candida is the leading cause of infection among pregnant women. This study was
aimed to determine the occurrence and antifungal susceptibility of Candida species
isolated from apparently healthy pregnant women receiving antenatal care at Bingham
University Teaching Hospital. High vaginal swab was inoculated onto Sabouraud
Dextrose Agar and Gram staining was carried out. Candida isolates were sub- cultured
on Himedia CHROM Candida differential agar and identified according to their color,
morphology, and appearance. Disc antifungal susceptibility test was carried out using
standard protocols. The occurrence rate of Vulvovaginal candidiasis (VVC) in this
study was 42.5%. In this study, Candia albicans was the most predominant Candida
species (51.2%) isolated. Pregnant women within the age range of 20-24 years had the
highest infection occurrence of 100% while the lowest occurrence of the infection
(25%) was observed among women within the age range of 40-44 years. There was a
significant relationship between age and VVC infection (P>0.05). In relation to
trimester, pregnant women in the second trimester had a high infection rate of 87.5%
while women in the third trimester had the least occurrence rate of 10.9%. There was a
significant relationship between Vulvovaginal candidiasis infection and trimester
(P>0.05). All Candida species were resistant to the antifungal drugs tested except for
Candida kefyr which was susceptible to fluconazole and voriconazole. Therefore,
early diagnosis and appropriate treatment among pregnant women receiving antenatal
care can reduce the infection and prevent complications during childbirth.
