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Antibacterial Activities of Annona senegalensis Pers. (Annonaceae) Extracts on Escherichia coli, Proteus mirabilis and Klebsiella pneumonia

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dc.contributor.author KOGGIE, Amos Zamfara
dc.contributor.author IHUMA, Jerome Obo
dc.contributor.author NYIKWAGH, Pamela Hembadoon
dc.date.accessioned 2024-05-16T08:09:14Z
dc.date.available 2024-05-16T08:09:14Z
dc.date.issued 2022-02-28
dc.identifier.issn 2456-7124
dc.identifier.uri http://localhost:8080/xmlui/handle/123456789/1112
dc.description.abstract This study investigated the presence of phytochemicals in the stem bark of Annona senegalensis. Phytochemicals extracted were alkanoid, flavonoid, tannin, saponin, and phenol, and the three extracts were: Cold Water Extract (CWE), Hot Water Extract (HWE) and Methanol Extracts (ME). The extracts of A. senegalensis were tested on Escherichia coli, Proteus mirabilis and Klebsiella pneumonia isolates in order to measure their antimicrobial and bactericidal activities. Irrespective of the method of extraction, the Minimum Inhibitory Concentration (MIC) was found to be 3.125 µl/ml. Minimum Bactericidal Concentration (MBC) required to kill the test organisms were also recorded. While CWE needs 100 µl/ml to kill each of the test organisms, HWE and ME both required concentrations of 50 µl/ml to completely kill E. coli and K. pneumonia. For P. mirabilis, the HWE needed a concentration of 400 µl/ml, while ME needed a concentration of 100 µl/ml to kill the organism. It was therefore concluded that the extracts of A. senegalensis had the potential to inhibit the growth (MIC) or even kill (MBC) the studied microorganisms at particular concentrations. This study is preliminary; therefore, an in vivo study should be undertaken to further test the potency and toxicity of the extracts with the view of standardizing the dosage and educating the traditional medicine practitioners on how to achieve healing without causing harm to patients. en_US
dc.language.iso en en_US
dc.publisher ASIAN JOURNAL OF BIOLOGY (AJOB) 14(2) en_US
dc.subject A. senegalensis en_US
dc.subject antibacterial en_US
dc.subject methanolic extracts en_US
dc.subject bactericidal en_US
dc.title Antibacterial Activities of Annona senegalensis Pers. (Annonaceae) Extracts on Escherichia coli, Proteus mirabilis and Klebsiella pneumonia en_US
dc.type Article en_US


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