Abstract:
In this paper, we propose a mathematical model
of malaria disease which involves Fractional
Differential Equations (FDEs) introducing the
effect of drug therapy and treatment rates. The
effective reproduction number ( eff
R ) is obtained
and computed using next generation method. The
eff
R was analytically evaluated for its sensitivity in
the model dynamics. It was proved that eff
R is a
strict decreasing function of drug therapy and
treatment parameters.