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Safety and Hypoglycaemic Properties of Aqueous Leaf Extract of Ocimum Gratissimum in Streptozotocin Induced Diabetic Rats.

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dc.contributor.author ADELAIYE, Alexander
dc.date.accessioned 2024-06-14T13:37:29Z
dc.date.available 2024-06-14T13:37:29Z
dc.date.issued 2006
dc.identifier.citation Egesie, U. G., Adelaiye, A. B., Ibu, J. O., & Egesie, O. J. (2006). Safety and hypoglycaemic properties of aqueous leaf extract of Ocimum gratissimum in streptozotocin induced diabetic rats. Nigerian Journal of Physiological Sciences, 21(1-2) en_US
dc.identifier.uri http://www.biolineinternational.org.br/njps
dc.identifier.uri http://localhost:8080/xmlui/handle/123456789/1980
dc.description.abstract The claim by Nigerian traditional herbal medicine practitioners that Ocimum gratissimum leaves have antidiabetic properties was investigated. Diabetes mellitus was induced with streptozotocin and graded doses of the aqueous leaf extract were administered orally to the experimentally diabetic rats for 28 days. Administration of the aqueous leaf extract caused a statistically significant reduction in plasma glucose level in streptozotocin induced diabetic rats. The extract appeared nontoxic as evidenced by normal serum levels of AST, ALT, ALP, TPT, ALB and bilirubin. These data appear to agree with claimed hypoglycaemic effects of Ocimum gratissimum en_US
dc.language.iso en en_US
dc.publisher Nigerian Journal of Physiological Sciences en_US
dc.relation.ispartofseries Volume 21;No 1-2
dc.subject Ocimum gratissimum en_US
dc.subject Diabetes mellitus en_US
dc.subject Hypoglycaemia en_US
dc.subject Liver enzymes en_US
dc.title Safety and Hypoglycaemic Properties of Aqueous Leaf Extract of Ocimum Gratissimum in Streptozotocin Induced Diabetic Rats. en_US
dc.type Article en_US


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