Phytochemical Constitutents and Antidiabetic  Property of Cola nitida Seeds on Alloxan Induced Diabetes Mellitus in Rats

EJIKE-ILIEMENE, Uju D; OKERE, O. Shekins

dc.contributor.author	EJIKE-ILIEMENE, Uju D
dc.contributor.author	OKERE, O. Shekins
dc.date.accessioned	2024-06-14T14:14:17Z
dc.date.available	2024-06-14T14:14:17Z
dc.date.issued	2014-11-19
dc.identifier.citation	19. Iliemene Uju Dorathy*, Shekins O. Okere, Eze Ejike Daniel and Liman Labaran Mubarak. (2014). Phytochemical Constitutents and Antidiabetic Property of Cola nitida Seeds on Alloxan-Induced Diabetes Mellitus in Rats. British Journal of Pharmaceutical Research. 4(23): 2631-2641.	en_US
dc.identifier.issn	2231-2919
dc.identifier.uri	http://localhost:8080/xmlui/handle/123456789/1996
dc.description.abstract	The seeds of Cola nitida were investigated for their anti-diabetic properties. The extracts were obtained by maceration in cold water. Alloxan was used to induce diabetes mellitus (DM) in the rats at 180mg/kg body weight and diabetes was confirmed after 48 hours. The Phytochemical analyses of the plants showed the presence of tannin, flavonoid, terpernoid, cardiac-gylcoside, and alkaloids. Anthraquinone and saponin were observed to be absent. Cola nitida was also observed to cause a reduction in blood glucose level from 599±0.667mg/dl (diabetic control) to 170±0.577mg/dl (extract treated group). The extract showed a significant (P<0.05) decrease of blood glucose level in alloxan induced diabetic rats. Cola nitida aqueous extract showed a higher level of potency when compared to a known anti-diabetic drug (Glanil).	en_US
dc.language.iso	en	en_US
dc.publisher	British Journal of Pharmaceutical Research	en_US
dc.relation.ispartofseries	Volume 4;NO. 23
dc.subject	Antidiabetic	en_US
dc.subject	diabetes mellitus	en_US
dc.subject	phytochemical	en_US
dc.subject	cola nitida	en_US
dc.title	Phytochemical Constitutents and Antidiabetic Property of Cola nitida Seeds on Alloxan Induced Diabetes Mellitus in Rats	en_US
dc.type	Article	en_US