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Browsing Department of Pharmacology & Toxicology by Title

Browsing Department of Pharmacology & Toxicology by Title

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  • Acute Toxicity Studies of Erythrophleum suaveolens in Albino Mice (Mus musculus) 
    IDYU, I. I.; KELA, S. L.; IDYU, V. C.; AKINYEDE, A.; BUILDERS, Modupe I.; OGBOLE E A., A.; RAMYIL, M. S.; OGUNDEKO, T. O. (INTERNATIONAL JOURNAL OF SCIENCE AND RESEARCH (IJSR) Vol. 3 No. 4, 2014-04)
    The activity of crude hydro-extract of stem bark of Erythrophleum suaveolens against Albino Mice was investigated. Extracted doses (50-300mg/kg) of the crude extract were administered. No mortality was recorded at low doses ...
  • Acute toxicity studies of locally cultivated Artemisia annua leaf extract in Rats 
    OGBOLE, Emmanuel Anebi; ISAIAH, Idyu; OGUNDEKO, Timothy; ASALU, Adedayo F.; BUILDERS, Modupe I.; AGUIYI, John (WORLD JOURNAL OF PHARMACEUTICAL SCIENCES (WJPS) Vol. 2 No. 12, 2014)
    Artemisia annua is a medicinal plant native to China and well known for its antiplasmodial, antirheumatic and anticancer properties. The acute toxicity, phytochemical screening and elemental analysis of hexane extract of ...
  • African Traditional Antimalarials: A Review 
    BUILDERS, Modupe I. (THE PHARMACEUTICAL AND CHEMICAL JOURNAL (PCJ) Vol. 4 No. 6, 2017)
    Traditional herbal medicines have been used to treat malaria for thousands of years in various parts of the world especially Africa. This review addresses medicinal plants used to treat malaria in traditional medicine from ...
  • Agelathus dodoneifolius (African Mistletoe): A Review 
    BUILDERS, Modupe I. (SOUTH ASIAN RESEARCH JOURNAL OF PHARMACEUTICAL SCIENCES (SSRJPS) Vol. 2 No. 3, 2020-06)
    Agelanthus dodoneifolius DC Danser synonym to Tapinanthus dodoneifolius, (family Loranthaceae) popularly called African mistletoe is a hemi-plant parasite used ethnomedicinally as a remedy for various diseases affecting ...
  • Analysis of Cigarette Puffs on Serum Cholesterol and Urea Level in Smokers and Non-Smokers with in VOM Area of Plateau State, Nigeria 
    AKANDE, T.; OGUNDEKO, T. O.; ARUKWE, L. C.; RAMYIL, M. S.; BUILDERS, Modupe I. (JOURNAL OF DENTAL AND MEDICAL SCIENCES (JDMS) Vol. 14 No. 3, 2015-03)
    A comparative study of Serum cholesterol and urea level of 100 subjects, consisting of 50 apparently smokers and 50 non-smokers as control was determined by Liebermann-Burchard reaction and Diacetylmonoxime method respectively. ...
  • Anti-Ulcer Activity of the Stem Bark of African Locust Bean Tree in Rats 
    BUILDERS, Modupe I.; BUILDERS, P. F.; OGUNDEKO, T. G. (INTERNATIONAL JOURNAL OF PHYTOTHERAPY RESEARCH (IJPTR) Vol.6 No.4, 2016)
    Parkiabiglobosa (Jacq.) R.Br. ex G. Don (family fabaceae) popularly called the African locust bean tree have been used traditionally in Nigeria and other West African rural communities to treat a variety of diseases including ...
  • Antimalarial Activity and Isolation of Phenolic Compound from Parkia biglobosa 
    BUILDERS, Modupe I.; ALEMIKA, Taiwo; AGUIYI, John (JOURNAL OF PHARMACY AND BIOLOGICAL SCIENCES (JPBS) Vol. 9 No. 3, 2014-06)
    Parkia biglobosa popularly called African locust bean tree is used traditionally for the treatment of malaria. Phenolic compounds were found to be the major antimalarial components of Parkia biglobosa .The aim of this work ...
  • Antimalarial Drug Use in the Paediatric Wards at Bingham University Teaching Hospital, Nigeria 
    BUILDERS, Modupe I.; OKORO, Ngozi (INTERNATIONAL JOURNAL OF PHARMACY AND PHARMACEUTICAL RESEARCH (IJPPR) Vol. 6 No. 1, 2016-04)
    The pattern of drug-use in cases of malaria infection either on prescription basis or self-medication can result in high incidence of resistant strain and therapeutic failure. The present study evaluates the pattern of ...
  • Antimalarial Drugs and COVID -19 
    BUILDERS, Modupe I.; SIMEON, Joseph Oyepata; OGUNDEKO, Timothy Olugbenga; BUILDERS, Philip (SUMERIANZ JOURNAL OF MEDICAL AND HEALTHCARE (SJMH) Vol. 3 No. 12, 2020)
    The coronavirus disease 2019 (COVID-19) is a novel virus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), that is ravaging the world. Therefore, the need to find new preventive and therapeutic drug ...
  • Antimalarial Drugs: A Review 
    BUILDERS, Modupe I. (INTERNATIONAL JOURNAL OF PHARMACY (IJP) Vol. 3 No. 1, 2013)
    Malaria causes about 400-900 million cases of fever and approximately 1-3 million deaths annually; this represents at least one death every 30 seconds. The vast majority of cases occur in children under the age of 5 years, ...
  • Antimalarial Phenolic Compounds in Africa: A Review 
    BUILDERS, Modupe I. (EUROPEAN JOURNAL OF BIOMEDICAL AND PHARMACEUTICAL SCIENCES (EJBPS) Vol. 6 No. 4, 2019)
    Malaria is currently a public health problem due to many factors such as parasite resistance, mosquito vector resistance, non-availability of vaccine and adverse reactions of antimalarial drugs. Traditional herbal medicines ...
  • Antiplasmodial Activities of Parkia Biglobosa Leaves: In Vivo and In Vitro Studies 
    BUILDERS, Modupe I.; WANNANG, Noel; AGUIYI, John (ANNALS OF BIOLOGICAL RESEARCH (ABR) Vol. 2 No. 4, 2011)
    The wide spread resistance of malaria parasites to conventional anti-malarials have stimulated the search for new drug entities especially those with new modes of action. The efficacy of the preparations of Parkia biglobosa ...
  • Antiplasmodial Potential of the African Mistletoe: Agelanthus dodoneifolius Polh and Wiens 
    BUILDERS, Modupe I.; UGURU, M. O.; AGUIYI, C. (INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES (IJPS) Vol. 74 No. 3, 2012-06)
    Preparations of Agelanthus dodoneifolius have been used in the traditional Nigerian medicine to treat malaria and this practice has remained till date without scientific validation. The antiplasmodial property of the water ...
  • Approaches to Pain Management: A Review 
    BUILDERS, Modupe I. (LUPINE ONLINE JOURNAL P HARMACOLOGY & CLINICAL RESEARCH (LOJPCR) Vol. 2 No.2, 2020-08)
    Pain mismanagement is associated with low recovery, high morbidity, increase hospital stay, decrease patient satisfaction, high costs of admission and adverse drug reactions due to inappropriate analgesic prescriptions. ...
  • Assessing Differential Impacts of COVID-19 on African Countries: A Comparative Study 
    JOSEPH, Oyepata Simeon; BUILDERS, Modupe I.; JOSEPH, Opeyemi Tosin; SABASTINE, Aliyu Zubairu (INTERNATIONAL JOURNAL OF RESEARCH AND INNOVATION IN APPLIED SCIENCE (IJRIAS) Vol. 5 No. 9, 2020-09)
    Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus. Most people who fall sick with COVID-19 experience mild to moderate symptoms and recover without special treatment. A number ...
  • Assessment of analgesic usage among the patients in Bingham University Teaching Hospital 
    BUILDERS, M.I; BASSI, P.U (INTERNATIONAL JOURNAL OF MEDICINE AND BIOMEDICAL RESEARCH (IJMBR) Vol. 6 No. 2, 2017-08)
    Background: Analgesics are the most commonly used drugs not only to relief of pain and fever but also for their anti-inflammatory effect. Inappropriate use of these drugs had led to increased risk of unwanted effects such ...
  • Assessment of Antimalarial Drug Use among the Patients in a Tertiary Hospital in Northern Part of Nigeria 
    BUILDERS, Modupe I.; OGBOLE, Emmanuel; PETER, Jonah Y. (CURRENT TRENDS IN DISEASE AND HEALTH Vol. 1, 2019)
    Aims: To assess the pattern of antimalarial drug use among the patients attending the teaching hospital in Jos North local Government of Nigeria. Study Design: Cross-sectional study. Place and Duration of Study: Tertiary ...
  • Assessment of Antimalarial Drug Use among the Patients in a Tertiary Hospital in Northern Part of Nigeria 
    BUILDERS, Modupe I.; OGBOLE, Emmanuel; PETER, Jonah Y. (INTERNATIONAL JOURNAL OF TROPICAL DISEASE & HEALTH (IJTDH) Vol. 3 No. 4, 2013)
    Aims: To assess the pattern of antimalarial drug use among the patients attending the teaching hospital in Jos North local Government of Nigeria. Study Design: Cross-sectional study. Place and Duration of Study: Tertiary ...
  • Assessment of Antimalarial Drug Use for Children among Mothers Attending Bingham University Teaching Hospital in Nigeria 
    BUILDERS, Modupe I.; AKANDE, Tunji; OGUNDEKO, Timothy (SKY JOURNAL OF MEDICINE AND MEDICAL SCIENCES (SJMMS) Vol. 4 No. 6, 2016-07)
    The aim of this study is to assess the use of antimalarial drug for children among mothers attending outpatient clinic in Bingham University Teaching Hospital. A cross-sectional study was carried out; information on ...
  • Assessment of Direct Causes and Costs of Medical Admissions in Bingham University Teaching Hospital – Jos, Nigeria 
    BASSI, Peter U.; BUILDERS, Modupe I.; OSARONOWEN, Egua Maxwel; MADUAGWUNA, Chinonye Anuli; IBRAHIM, Abdulmumini A.; DANKYAU, Musa (SAHEL MEDICAL JOURNAL (SMJ) Vol. 20 No. 4, 2017-12)
    Background: As health‑care costs continue to rise and the population ages, an individual Nigerian continues to experience financial hardship in settling medical bills, especially when health insurance schemes are still far ...

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