Department of Pharmacology & Toxicology: Recent submissions

  • Effect of Ethanol Leaf Extract of Pterocarpus santalinus Extract on Kidney of Wister Rats 
    HARUNA, Wazis Chama; SIMEON, Joseph Oyepata; BUILDERS, Modupe I.; TOSIN, Joseph Opeyemi (NIGERIAN BIOMEDICAL SCIENCE JOURNAL (NBSJ) Vol. 17 No. 1, 2020)
    Aim/Introduction: plant has been the primary and initial source of drug development. Plant has been used for medicinal purposes long before prehistoric period. The aim of this study is to evaluate the effect of Pterocarpus ...
  • EFFECT OF ETHANOL LEAF EXTRACT OF Cassia angustifolia EXTRACT ON HEART AND LIPID PROFILE OF WISTER RATS 
    HARUNA, Wazis Chama; SIMEON, Joseph Oyepata; BUILDERS, Modupe I.; TOSIN, Joseph Opeyemi (AFRICAN JOURNAL OF PHARMACEUTICAL RESEARCH & DEVELOPMENT (AJPRD) Vol. 12 No.1, 2020)
    The human heart is an organ that pumps blood throughout the body via the circulatory system, supplying oxygen and nutrients to the tissues and removing carbon dioxide and other wastes. Damage to tissue or cells of the heart ...
  • Effect of Ethanol Leaf Extract of Cassia Angustifolia Extract on Liver of Wister Rats 
    JOSEPH, O.S.; BUILDERS, Modupe I.; EMEM, E.U.; JOSEPH, O.T. (GLOBAL SCIENTIFIC JOURNAL (GSJ) Vol. 7 No. 10, 2019-10)
    Background/Aim: The liver does many important things including makes bile, which helps carry away waste and break down fats in the small intestine during digestion makes certain proteins for blood plasma makes cholesterol ...
  • Effect of Administration Ethanol Leaf Extract of Terminalia Chebula on Liver of Wister Rat 
    SIMEON, Joseph Oyepata; BUILDERS, Modupe I.; HARUNA, Wazis Chama; TOSIN, Joseph Opeyemi; ZUBAIRU, Sabastine Aliyu; LUBO, Musa Tabitha; SADIQ, Moh’d A. (INTERNATIONAL JOURNAL OF RESEARCH AND SCIENTIFIC INNOVATION (IJRSI) Vol.6 No. 7, 2019-07)
    Introduction/Aim: Subacute toxicity tests are intended to evaluate the toxicity of the chemical after repeated administration and also to help in establishing doses for the longer-term subchronic studies. Plant has been ...
  • Drug Utilization Study in Bingham University Teaching Hospital 
    BUILDERS, Modupe I.; OGBOLE, Emmanuel; AKANDE, Tunji; OGUNDEKO, Timothy (DONNISH JOURNAL OF MEDICINE AND MEDICAL SCIENCES (DJMMS) Vol. 2 No. 5, 2015-06)
    Background: The World Health Organization (WHO) has defined drug utilization research as the marketing, distribution, prescription, and use of drugs in a society, with special emphasis on the resulting medical, social, and ...
  • Assessment of the Intrinsic and Stability Properties of the Freeze-Dried and Formulated Extract of Hibiscus Sabdariffa Linn. (Malvaceae) 
    BUILDERS, Philip F.; EZEOBI, Chukwuemeka R.; TARFA, Florence D.; BUILDERS, Modupe I. (AFRICAN JOURNAL OF PHARMACY AND PHARMACOLOGY (AJPP) Vol. 4 No. 6, 2010-06)
    Water extract of the calyces of Hibiscus sabdariffa Linn (Malvaceae) is used widely as a food additive and refreshing drink with proven medicinal benefits, which are attributed to its phytochemical constituents. Relevant ...
  • Assessment of Direct Causes and Costs of Medical Admissions in Bingham University Teaching Hospital – Jos, Nigeria 
    BASSI, Peter U.; BUILDERS, Modupe I.; OSARONOWEN, Egua Maxwel; MADUAGWUNA, Chinonye Anuli; IBRAHIM, Abdulmumini A.; DANKYAU, Musa (SAHEL MEDICAL JOURNAL (SMJ) Vol. 20 No. 4, 2017-12)
    Background: As health‑care costs continue to rise and the population ages, an individual Nigerian continues to experience financial hardship in settling medical bills, especially when health insurance schemes are still far ...
  • Assessment of Antimalarial Drug Use for Children among Mothers Attending Bingham University Teaching Hospital in Nigeria 
    BUILDERS, Modupe I.; AKANDE, Tunji; OGUNDEKO, Timothy (SKY JOURNAL OF MEDICINE AND MEDICAL SCIENCES (SJMMS) Vol. 4 No. 6, 2016-07)
    The aim of this study is to assess the use of antimalarial drug for children among mothers attending outpatient clinic in Bingham University Teaching Hospital. A cross-sectional study was carried out; information on ...
  • Assessment of Antimalarial Drug Use among the Patients in a Tertiary Hospital in Northern Part of Nigeria 
    BUILDERS, Modupe I.; OGBOLE, Emmanuel; PETER, Jonah Y. (INTERNATIONAL JOURNAL OF TROPICAL DISEASE & HEALTH (IJTDH) Vol. 3 No. 4, 2013)
    Aims: To assess the pattern of antimalarial drug use among the patients attending the teaching hospital in Jos North local Government of Nigeria. Study Design: Cross-sectional study. Place and Duration of Study: Tertiary ...
  • Assessment of analgesic usage among the patients in Bingham University Teaching Hospital 
    BUILDERS, M.I; BASSI, P.U (INTERNATIONAL JOURNAL OF MEDICINE AND BIOMEDICAL RESEARCH (IJMBR) Vol. 6 No. 2, 2017-08)
    Background: Analgesics are the most commonly used drugs not only to relief of pain and fever but also for their anti-inflammatory effect. Inappropriate use of these drugs had led to increased risk of unwanted effects such ...
  • Assessing Differential Impacts of COVID-19 on African Countries: A Comparative Study 
    JOSEPH, Oyepata Simeon; BUILDERS, Modupe I.; JOSEPH, Opeyemi Tosin; SABASTINE, Aliyu Zubairu (INTERNATIONAL JOURNAL OF RESEARCH AND INNOVATION IN APPLIED SCIENCE (IJRIAS) Vol. 5 No. 9, 2020-09)
    Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus. Most people who fall sick with COVID-19 experience mild to moderate symptoms and recover without special treatment. A number ...
  • Approaches to Pain Management: A Review 
    BUILDERS, Modupe I. (LUPINE ONLINE JOURNAL P HARMACOLOGY & CLINICAL RESEARCH (LOJPCR) Vol. 2 No.2, 2020-08)
    Pain mismanagement is associated with low recovery, high morbidity, increase hospital stay, decrease patient satisfaction, high costs of admission and adverse drug reactions due to inappropriate analgesic prescriptions. ...
  • Anti-Ulcer Activity of the Stem Bark of African Locust Bean Tree in Rats 
    BUILDERS, Modupe I.; BUILDERS, P. F.; OGUNDEKO, T. G. (INTERNATIONAL JOURNAL OF PHYTOTHERAPY RESEARCH (IJPTR) Vol.6 No.4, 2016)
    Parkiabiglobosa (Jacq.) R.Br. ex G. Don (family fabaceae) popularly called the African locust bean tree have been used traditionally in Nigeria and other West African rural communities to treat a variety of diseases including ...
  • Antiplasmodial Potential of the African Mistletoe: Agelanthus dodoneifolius Polh and Wiens 
    BUILDERS, Modupe I.; UGURU, M. O.; AGUIYI, C. (INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES (IJPS) Vol. 74 No. 3, 2012-06)
    Preparations of Agelanthus dodoneifolius have been used in the traditional Nigerian medicine to treat malaria and this practice has remained till date without scientific validation. The antiplasmodial property of the water ...
  • Antiplasmodial Activities of Parkia Biglobosa Leaves: In Vivo and In Vitro Studies 
    BUILDERS, Modupe I.; WANNANG, Noel; AGUIYI, John (ANNALS OF BIOLOGICAL RESEARCH (ABR) Vol. 2 No. 4, 2011)
    The wide spread resistance of malaria parasites to conventional anti-malarials have stimulated the search for new drug entities especially those with new modes of action. The efficacy of the preparations of Parkia biglobosa ...
  • Antimalarial Phenolic Compounds in Africa: A Review 
    BUILDERS, Modupe I. (EUROPEAN JOURNAL OF BIOMEDICAL AND PHARMACEUTICAL SCIENCES (EJBPS) Vol. 6 No. 4, 2019)
    Malaria is currently a public health problem due to many factors such as parasite resistance, mosquito vector resistance, non-availability of vaccine and adverse reactions of antimalarial drugs. Traditional herbal medicines ...
  • Antimalarial Drugs and COVID -19 
    BUILDERS, Modupe I.; SIMEON, Joseph Oyepata; OGUNDEKO, Timothy Olugbenga; BUILDERS, Philip (SUMERIANZ JOURNAL OF MEDICAL AND HEALTHCARE (SJMH) Vol. 3 No. 12, 2020)
    The coronavirus disease 2019 (COVID-19) is a novel virus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), that is ravaging the world. Therefore, the need to find new preventive and therapeutic drug ...
  • Antimalarial Drugs: A Review 
    BUILDERS, Modupe I. (INTERNATIONAL JOURNAL OF PHARMACY (IJP) Vol. 3 No. 1, 2013)
    Malaria causes about 400-900 million cases of fever and approximately 1-3 million deaths annually; this represents at least one death every 30 seconds. The vast majority of cases occur in children under the age of 5 years, ...
  • Antimalarial Drug Use in the Paediatric Wards at Bingham University Teaching Hospital, Nigeria 
    BUILDERS, Modupe I.; OKORO, Ngozi (INTERNATIONAL JOURNAL OF PHARMACY AND PHARMACEUTICAL RESEARCH (IJPPR) Vol. 6 No. 1, 2016-04)
    The pattern of drug-use in cases of malaria infection either on prescription basis or self-medication can result in high incidence of resistant strain and therapeutic failure. The present study evaluates the pattern of ...
  • Antimalarial Activity and Isolation of Phenolic Compound from Parkia biglobosa 
    BUILDERS, Modupe I.; ALEMIKA, Taiwo; AGUIYI, John (JOURNAL OF PHARMACY AND BIOLOGICAL SCIENCES (JPBS) Vol. 9 No. 3, 2014-06)
    Parkia biglobosa popularly called African locust bean tree is used traditionally for the treatment of malaria. Phenolic compounds were found to be the major antimalarial components of Parkia biglobosa .The aim of this work ...

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