Abstract:
: A series of 4-aryl-2-aminothiazole were synthesized with an objective to develop novel and potent coupling
components of synthetic origin as well as in dye synthesis. The required derivatives of 4-phenylsubstituted-2-
aminothiazole were synthesized via a multicomponent condensation between thiourea, acetophenone and iodine. The
intermediates were obtained using acetophenone and various substituted aldehydes to synthesize the intermediates
which on cyclization with sulphur yielded the final products. Synthesized compounds were purified, characterized using
UV-Visible Spectrophotometer, Infra–red, GC-MS Spectrometer and NMR. They were also evaluated for their spectra
properties. All the synthesized intermediates exhibited moderate to significant properties. They were found to possess
good coupling properties as well as high degree of brightness and a colour deepening effect compared to other
heterocyclic couplers obtained from aniline and anthraquinone dyes.
