Abstract:
Antibiotic resistance has
become a significant
public health problem;
thus, it is highly
essential that new
antibiotics continue to be
developed. Recentlystudies have been carried
out
to
ascertain
the
antimicrobial benefits of
essential oils and how
they can be incorporated
into the fight against
infections and infectious
diseases. This research
was carried out with the
purpose of verifying the
effectiveness
of
the
essential oil of lemongrass
for
the
pathogenic
treatment of
organisms.
Lemongrass
oil
was
investigated for activity
against two gram positive
organisms (Streptococcus
pneumonia
and
a
Staphylococcus aureus),
two
gram
organisms
negative
(Escherichia
coli and Salmonella typhi)
and
fungi
albicans)
(Candida
using
Diffusion
Agar
Method and
Broth Dilution Method.
Minimum
inhibitory
concentration (MIC) and
minimum
bactericidal
concentration (MBC) were
determined by the Broth
Dilution
Method.
Lemongrass was found to
be effective against all the
test
organisms.
results
depicted
The
that
Lemongrass extracted oil
generated
different
inhibition
zones
diameters (IZDs) that
ranged from 6-19.75mm,
which
were
dose
independent. The tested
organisms were found to
be
inhibited
by
lemongrass oil even at low
concentrations. Also, the
test
organisms
were
inhibited by Lemon grass
oil at lower concentrations
in Broth Dilution Method
as compared to Agar
Diffusion Method. Thus, it
is
concluded
that
lemongrass oil would be
helpful in the treatment of
emerging
infections
caused by susceptible
pathogenic organisms.
