Abstract:
Background: Mucoepidermoid carcinoma (MEC), a tumour previously believed to occur exclusively
in the major salivary glands, was atypically recognized in the lacrimal gland. Few ophthalmologists are
familiar with this rare neoplasm. Aim: This case is being reported for its rarity and the association with
human immunodeficiency virus (HIV). Case Presentation: High-grade MEC of the lacrimal gland of
the right eye was diagnosed in an orbital exenteration specimen of a 60-year-old HIV-positive man. He
presented to the eye unit of a mission hospital in Jos, Nigeria with significant visual impairment in the
right eye and a rapidly growing painful superolateral orbital mass. The tumour invaded and completely
obliterated the anterior chamber. The lens, ciliary body, and iris were displaced posteriorly but were free
from tumour infiltration. The tumour was exenterated, and the patient was subsequently referred for
adjuvant radiotherapy. No evidence of recurrence or metastasis has been noted 15 months post-surgery.
Conclusion: Early and decisive surgical intervention in a case of high-grade MEC of the lacrimal gland
is crucial in forestalling local invasion as well as distant metastasis. Because of the possibility of local
recurrence, adjuvant radiotherapy is required and close follow-up of the patient is warranted
