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Now showing items 1-20 of 133

MENACE OF FAKE AND COUNTERFEIT DRUGS

ALFA, John (NEW NIGERIA, 1990-01-30)

A final year student of Agricultural extension was in heat of preparation for sessional examinations when a bout of fever unexpectedly unnerved him. Throughout the night he shivered ceaselessly like a hunch of seed being ...
Towards self-Sufficiency in Pharmaceuticals

ALFA, John (ABUJA NEWSDAY, 1990-08-15)

Most of our Pharmaceutical manufacturing agencies are yet to be 'original' in terms of finished products and this flaw has turned our nation into a dumping ground for fake and adulterated drugs.
Isolation and Physiotechnical Properties of Grades of Cellulose Derived from a Novel Source, Sorghum bicolor

ALFA, John (Journal of Pharmaceutical Research and Development, 2000)

Sodium hydroxide de-lignified cc-Cellulose obtained from Sorphum bicolor was modified to the microcrystalline form by appropriate treatment with a mineral acid. The grades of cellulose were subejcted to preliminary ...
Cissus stem gum as potential dispersant in pharmaceutical liquid systems: rheological characterization

ALFA, John (Bollettino Chimico Farmaceutico, 2001)

A Co-axial viscometer, the Haake-Rotovisco, was used studying the rheological behaviour of aqueous dispersion of cissus stem gum. At concentrations of 4% w/v and above, the mucilage is both pseudoplastic and thixotropic. ...
Design of a New Compressible Metronidazole Powder: Co-precipitation with Ovalbumin

ALFA, John (Journal of Phytomedicine and Therapeutics, 2001)

Metronidazole powder was co-precipitated with egg albumin solution al concentrations of IO to 40 % w/v. The batch treated with 15 % of the ovalbumin was compared with metronidazole granulated with starch. Brittle Fracture ...
Cissus Stem Gumas Potential Dispersantin Pharmaceutical Liquid Systems Suspending and Emulsifying Properties

ALFA, John (Bollettino Chimico Farmaceutico, 2001)

The emulsifying and suspending properties of a new gum derived from the stem of cissus rufescence family Amphelidaceae were studied. Stability of the liquid paraffin emulsions prepared using this mucilaginous substance was ...
Application of Silicified Microcrystalline Cellulose in the formulation of Metronidazole Tablets

ALFA, John (Pharmaceutical Technology Conference Liverpool, 2001)

The influence of Silicified Microcystalline Cellulose on the powder, compaction and tableting properties of metronidazole was investigated. The study employed a medium grade of Silicifed Microcystalline Cellulose, commercially ...
Direct Compression Properties of Microcrystalline Cellulose and Its Silicified Product

ALFA, John (East and Central African Journal of Pharmaceutical Sciences, 2004)

The influence of silicified microcrystalline cellulose (SMCC) on the flow, compaction and tableting properties of metronidazole powder was investigated. The study compared medium grades of both SMCC and standard microcrystalline ...
Preparation and Evaluation of Mucinated Sodium Alginate Microparticles for Oral Delivery of Insulin

BUILDERS, Philip F.; KUNLE, Olobayo O.; OKPAKU, Larry C.; BUILDERS, Modupe I.; ATTAMA, Anthony A.; ADIKWU, Michael U. (EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (EJPB) Vol. 70, 2008)

Effective oral insulin delivery remains a challenge to the pharmaceutical industry. In this study, insulinloaded microparticles for oral delivery were prepared with mucin and sodium alginate combined at different ratios ...
Effect of Lubricants on Flow Properties and Tablet Strength of Silicified Microcrystalline Cellulose

ALFA, John (FABAD Journal of Pharmaceutical Sciences, 2008)

The effects of magnesium stearate, sodium lauryl sulphate (SLS) and talc as lubricants on some powder and tablet properties of silicified microcrystalline cellulose (SMCC) were studied. Single and binary blends of talc, ...
Assessment of the Intrinsic and Stability Properties of the Freeze-Dried and Formulated Extract of Hibiscus Sabdariffa Linn. (Malvaceae)

BUILDERS, Philip F.; EZEOBI, Chukwuemeka R.; TARFA, Florence D.; BUILDERS, Modupe I. (AFRICAN JOURNAL OF PHARMACY AND PHARMACOLOGY (AJPP) Vol. 4 No. 6, 2010-06)

Water extract of the calyces of Hibiscus sabdariffa Linn (Malvaceae) is used widely as a food additive and refreshing drink with proven medicinal benefits, which are attributed to its phytochemical constituents. Relevant ...
Antiplasmodial Activities of Parkia Biglobosa Leaves: In Vivo and In Vitro Studies

BUILDERS, Modupe I.; WANNANG, Noel; AGUIYI, John (ANNALS OF BIOLOGICAL RESEARCH (ABR) Vol. 2 No. 4, 2011)

The wide spread resistance of malaria parasites to conventional anti-malarials have stimulated the search for new drug entities especially those with new modes of action. The efficacy of the preparations of Parkia biglobosa ...
Prescription Patterns of Analgesics in a Community Hospital in Nsukka

BUILDERS, Modupe I.; OKONTA, J. M.; AGUWA, C. N. (JOURNAL OF PHARMACUETICAL SCIENCE AND RESEARCH (JPSR) Vol. 3 No. 12, 2011)

Analgesics are one of the most prescribed groups of drugs. Faulty prescription patterns in analgesics often results in aggravated side effects and drug interactions leading to serious adverse drug reactions. In this study ...
Patients’ Attitudes Towards Analgesic Usage in Nsukka Community

BUILDERS, Modupe I.; AGUWA, Cletus Nze (SCHOLARS RESEARCH LIBRARY (SRL) Vol. 4 No. 2, 2012)

Analgesics, though relatively safe, are among the commonly used and abused drugs. Many people concomitantly take the same analgesics of different brands thereby contributing to analgesic nephropathy. In this study we ...
Toxicity Studies of the Extracts of Parkia Biglobosa Stem Bark in Rats

BUILDERS, Modupe I.; ISICHIE, C. O.; AGUIYI, J. C. (BRITISH JOURNAL OF PHARMACEUTICAL RESEARCH (BJPR) Vol. 2 No. 1, 2012)

Extracts of Parkia biglobosa stem bark is used in Nigerian traditional medicine (NTM) to treat malaria, diarrhea and pains. To establish the toxicity profile of the medicine such parameters as the lethal dose (LD50) as ...
Antiplasmodial Potential of the African Mistletoe: Agelanthus dodoneifolius Polh and Wiens

BUILDERS, Modupe I.; UGURU, M. O.; AGUIYI, C. (INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES (IJPS) Vol. 74 No. 3, 2012-06)

Preparations of Agelanthus dodoneifolius have been used in the traditional Nigerian medicine to treat malaria and this practice has remained till date without scientific validation. The antiplasmodial property of the water ...
Assessment of Antimalarial Drug Use among the Patients in a Tertiary Hospital in Northern Part of Nigeria

BUILDERS, Modupe I.; OGBOLE, Emmanuel; PETER, Jonah Y. (INTERNATIONAL JOURNAL OF TROPICAL DISEASE & HEALTH (IJTDH) Vol. 3 No. 4, 2013)

Aims: To assess the pattern of antimalarial drug use among the patients attending the teaching hospital in Jos North local Government of Nigeria. Study Design: Cross-sectional study. Place and Duration of Study: Tertiary ...
Antimalarial Drugs: A Review

BUILDERS, Modupe I. (INTERNATIONAL JOURNAL OF PHARMACY (IJP) Vol. 3 No. 1, 2013)

Malaria causes about 400-900 million cases of fever and approximately 1-3 million deaths annually; this represents at least one death every 30 seconds. The vast majority of cases occur in children under the age of 5 years, ...
Evaluation of Antifungal Activities of the Crude Leaf Extracts of Mitracarpus vilosus

ASOGWA, Ifeoma .S. (African Journal of Pharmaceutical Research & Development, 2013)

The antifungal activities of fractions of the leaf extract of Mitracarpus vilosus were evaluated in comparison with some standard antifungal drugs (ketoconazole, clotrimazole, fluconazole, nystatin and tioconazole), ...
Fighting faking and counterfeiting: Lessons from the Nigerian NASS Clinic

ALFA, John (International Journal of Drug Development and Research, 2013-07)

Abstract: Faking and counterfeiting remains a major barrier to the management and control of important diseases that plague developing countries. As well as constituting significant risk to patients and consumers, it also ...

Now showing items 1-20 of 133

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