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Browsing Faculty of Pharmaceutical Sciences by Title

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  • 60-Day Assessment of Mr. Flush® Cleanser on Hematological indices and Kidney Histoarchitecture in Exposed Wistar Rats 
    Uduak, Peter Ise; Famojuro, Tayo I.; Johnson, O.J; Sebastine, A. Z.; Ibrahim, A.M.; Williams, Ujah; Builders, M.I (Journal of pharmaceutical science and research, 2023)
    ct Aim: there is a surge in herbal product sales with less adequate information on their safety. The toxicity concerns of Mr. Flush® polyherbal formulation on hematological and biochemical parameters was investigated in ...
  • Acute Toxicity Studies of Erythrophleum suaveolens in Albino Mice (Mus musculus) 
    IDYU, I. I.; KELA, S. L.; IDYU, V. C.; AKINYEDE, A.; BUILDERS, Modupe I.; OGBOLE E A., A.; RAMYIL, M. S.; OGUNDEKO, T. O. (INTERNATIONAL JOURNAL OF SCIENCE AND RESEARCH (IJSR) Vol. 3 No. 4, 2014-04)
    The activity of crude hydro-extract of stem bark of Erythrophleum suaveolens against Albino Mice was investigated. Extracted doses (50-300mg/kg) of the crude extract were administered. No mortality was recorded at low doses ...
  • ACUTE TOXICITY STUDIES OF ETHYL ACETATE METABOLIC EXTRACT OF ENDOPHYTIC FUNGI ISOLATE OF MITRCARPUS SCABER 
    Asogwa, Ifeoma S.; Agbo, Anthony C.; Udauk, Peter I.; Ibezim, Chinedu E.; Attama, Anthony A. (TIMBOU-AFRICA ACADEMIC PUBLICATIONS, 2023-11)
    Safety or toxicity assessment of newly discovered endophytes with potential therapeutic applications is very crucial prior to their approval for human use. This is to ascertain the possible undesirable outcomes ...
  • Acute toxicity studies of locally cultivated Artemisia annua leaf extract in Rats 
    OGBOLE, Emmanuel Anebi; ISAIAH, Idyu; OGUNDEKO, Timothy; ASALU, Adedayo F.; BUILDERS, Modupe I.; AGUIYI, John (WORLD JOURNAL OF PHARMACEUTICAL SCIENCES (WJPS) Vol. 2 No. 12, 2014)
    Artemisia annua is a medicinal plant native to China and well known for its antiplasmodial, antirheumatic and anticancer properties. The acute toxicity, phytochemical screening and elemental analysis of hexane extract of ...
  • African Traditional Antimalarials: A Review 
    BUILDERS, Modupe I. (THE PHARMACEUTICAL AND CHEMICAL JOURNAL (PCJ) Vol. 4 No. 6, 2017)
    Traditional herbal medicines have been used to treat malaria for thousands of years in various parts of the world especially Africa. This review addresses medicinal plants used to treat malaria in traditional medicine from ...
  • Agelathus dodoneifolius (African Mistletoe): A Review 
    BUILDERS, Modupe I. (SOUTH ASIAN RESEARCH JOURNAL OF PHARMACEUTICAL SCIENCES (SSRJPS) Vol. 2 No. 3, 2020-06)
    Agelanthus dodoneifolius DC Danser synonym to Tapinanthus dodoneifolius, (family Loranthaceae) popularly called African mistletoe is a hemi-plant parasite used ethnomedicinally as a remedy for various diseases affecting ...
  • Analysis of Cigarette Puffs on Serum Cholesterol and Urea Level in Smokers and Non-Smokers with in VOM Area of Plateau State, Nigeria 
    AKANDE, T.; OGUNDEKO, T. O.; ARUKWE, L. C.; RAMYIL, M. S.; BUILDERS, Modupe I. (JOURNAL OF DENTAL AND MEDICAL SCIENCES (JDMS) Vol. 14 No. 3, 2015-03)
    A comparative study of Serum cholesterol and urea level of 100 subjects, consisting of 50 apparently smokers and 50 non-smokers as control was determined by Liebermann-Burchard reaction and Diacetylmonoxime method respectively. ...
  • Anti-Ulcer Activity of the Stem Bark of African Locust Bean Tree in Rats 
    BUILDERS, Modupe I.; BUILDERS, P. F.; OGUNDEKO, T. G. (INTERNATIONAL JOURNAL OF PHYTOTHERAPY RESEARCH (IJPTR) Vol.6 No.4, 2016)
    Parkiabiglobosa (Jacq.) R.Br. ex G. Don (family fabaceae) popularly called the African locust bean tree have been used traditionally in Nigeria and other West African rural communities to treat a variety of diseases including ...
  • Antibiotics prescribing pattern for respiratory tract infections: findings from a secondary healthcare facility in Abuja 
    ALFA, John (International Journal of Pharmacy Practice, 2015-04)
    Rational use of medicines is a concept developed to facilitate the provision of safe medicines and quality healthcare. Key elements include rational prescribing, dispensing and use of medicines. Understanding prescribing ...
  • Antimalarial Activity and Isolation of Phenolic Compound from Parkia biglobosa 
    BUILDERS, Modupe I.; ALEMIKA, Taiwo; AGUIYI, John (JOURNAL OF PHARMACY AND BIOLOGICAL SCIENCES (JPBS) Vol. 9 No. 3, 2014-06)
    Parkia biglobosa popularly called African locust bean tree is used traditionally for the treatment of malaria. Phenolic compounds were found to be the major antimalarial components of Parkia biglobosa .The aim of this work ...
  • Antimalarial Drug Use in the Paediatric Wards at Bingham University Teaching Hospital, Nigeria 
    BUILDERS, Modupe I.; OKORO, Ngozi (INTERNATIONAL JOURNAL OF PHARMACY AND PHARMACEUTICAL RESEARCH (IJPPR) Vol. 6 No. 1, 2016-04)
    The pattern of drug-use in cases of malaria infection either on prescription basis or self-medication can result in high incidence of resistant strain and therapeutic failure. The present study evaluates the pattern of ...
  • Antimalarial Drugs and COVID -19 
    BUILDERS, Modupe I.; SIMEON, Joseph Oyepata; OGUNDEKO, Timothy Olugbenga; BUILDERS, Philip (SUMERIANZ JOURNAL OF MEDICAL AND HEALTHCARE (SJMH) Vol. 3 No. 12, 2020)
    The coronavirus disease 2019 (COVID-19) is a novel virus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), that is ravaging the world. Therefore, the need to find new preventive and therapeutic drug ...
  • Antimalarial Drugs: A Review 
    BUILDERS, Modupe I. (INTERNATIONAL JOURNAL OF PHARMACY (IJP) Vol. 3 No. 1, 2013)
    Malaria causes about 400-900 million cases of fever and approximately 1-3 million deaths annually; this represents at least one death every 30 seconds. The vast majority of cases occur in children under the age of 5 years, ...
  • Antimalarial Phenolic Compounds in Africa: A Review 
    BUILDERS, Modupe I. (EUROPEAN JOURNAL OF BIOMEDICAL AND PHARMACEUTICAL SCIENCES (EJBPS) Vol. 6 No. 4, 2019)
    Malaria is currently a public health problem due to many factors such as parasite resistance, mosquito vector resistance, non-availability of vaccine and adverse reactions of antimalarial drugs. Traditional herbal medicines ...
  • Antimicrobial Activities of the Leaf Extracts of Ficus sycomorus Linn. on Helicobacter pylori and Citrobacter freundii 
    IHUMA, Jerome; KOGGIE, A.Z; FAMOJURO, Tayo I.; Ugboji, L.O (Asian Journal of Biology, 2022-08-25)
    Aims: The aim of this study is to determine the antimicrobial activities of Ficus sycomorus leave extract on selected bacteria. Phytochemical screening showed the presence of tannins, saponins, alkaloids and flavonoids, ...
  • Antimicrobial Effects of the Stem Bark Extracts of Parkia biglobosa (Jacq.) G. Don on Escherichia coli and Staphylococcus aureus 
    Ihuma, J. O; Kure, S .; Famojuro, Tayo I. (Asian Journal of Biology, 2022-12-21)
    Aims: This work aimed to evaluate the antimicrobial potential of the stem bark extracts of P. biglobosa on selected bacteria species, Escherichia coli, and Staphylococcus aureus. Place and Duration of Study: Microbiology ...
  • Antiplasmodial Activities of Parkia Biglobosa Leaves: In Vivo and In Vitro Studies 
    BUILDERS, Modupe I.; WANNANG, Noel; AGUIYI, John (ANNALS OF BIOLOGICAL RESEARCH (ABR) Vol. 2 No. 4, 2011)
    The wide spread resistance of malaria parasites to conventional anti-malarials have stimulated the search for new drug entities especially those with new modes of action. The efficacy of the preparations of Parkia biglobosa ...
  • Antiplasmodial Potential of the African Mistletoe: Agelanthus dodoneifolius Polh and Wiens 
    BUILDERS, Modupe I.; UGURU, M. O.; AGUIYI, C. (INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES (IJPS) Vol. 74 No. 3, 2012-06)
    Preparations of Agelanthus dodoneifolius have been used in the traditional Nigerian medicine to treat malaria and this practice has remained till date without scientific validation. The antiplasmodial property of the water ...
  • Application of Silicified Microcrystalline Cellulose in the formulation of Metronidazole Tablets 
    ALFA, John (Pharmaceutical Technology Conference Liverpool, 2001)
    The influence of Silicified Microcystalline Cellulose on the powder, compaction and tableting properties of metronidazole was investigated. The study employed a medium grade of Silicifed Microcystalline Cellulose, commercially ...
  • Approaches to Pain Management: A Review 
    BUILDERS, Modupe I. (LUPINE ONLINE JOURNAL P HARMACOLOGY & CLINICAL RESEARCH (LOJPCR) Vol. 2 No.2, 2020-08)
    Pain mismanagement is associated with low recovery, high morbidity, increase hospital stay, decrease patient satisfaction, high costs of admission and adverse drug reactions due to inappropriate analgesic prescriptions. ...

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