• Evaluation of Anxiolytic Activity of Ethanolic Extract of Thymus vulgaris Leaves Using Elevated Plus Maze [EPM] Test 

  Uduak, Peter Ise (Subscription agency, 2023)

  The most common group of psychiatric diseases are anxiety disorders, thus there is increase need for anxiolytics as a result of increasingly paced world. The current anxiolytics are characterized by serious adverse effects ...
• Evaluation of hepatoprotective activity of the aqueous extract of Vitis vinifera against acetaminophen-induced liver damage in rats 

  UDUAK, Peter I. (Magna Scientia, 2023-07-24)

  In this study we evaluated the hepatotoxicity activity of Vitis vinifera in acetaminophen induced liver damage in rats. Five (5) Groups of rats were used for the study, Group 1 received normal saline (1ml /kg, p.o), Group ...
• Toxicological Study of the Effect of Ethanol Leaf Extract of Pterocarpus santalinus Extract on Liver of Wister Rats 

  HARUNA, Wazis Chama; BUILDERS, Modupe I.; SIMEON, Joseph Oyepata; TOSIN, Joseph Opeyemi (NIGERIAN BIOMEDICAL SCIENCE JOURNAL (NBSJ) Vol. 17 No. 1, 2020)

  Aim/introduction: The use of medicinal plants has attained a commanding role in health system all over the world. Pterocarpus santalinus is a plant common in Asia and Africa has been used traditionally in management of ...
• Toxicity Studies of the Extracts of Parkia Biglobosa Stem Bark in Rats 

  BUILDERS, Modupe I.; ISICHIE, C. O.; AGUIYI, J. C. (BRITISH JOURNAL OF PHARMACEUTICAL RESEARCH (BJPR) Vol. 2 No. 1, 2012)

  Extracts of Parkia biglobosa stem bark is used in Nigerian traditional medicine (NTM) to treat malaria, diarrhea and pains. To establish the toxicity profile of the medicine such parameters as the lethal dose (LD50) as ...
• Toxicity Study of Ethanol Leaf Extract of Ocimum Canum on Heart and Lipid Profile of Wister Rats 

  JOSEPH, O. S.; BUILDERS, Modupe I.; JOSEPH, O. T; ARIAHU, E. C.; ZUBAIRU, S. A.; MUSA, T.; OYEPATA, P. J (INTERNATIONAL JOURNAL OF CURRENT ADVANCED RESEARCH (IJCAR) Vol. 8 No. 5, 2019-05)

  Background/Aim: The human heart is an organ that pumps blood throughout the body via the circulatory system, supplying oxygen and nutrients to the tissues and removing carbon dioxide and other wastes. Several substances ...
• Toxicity studies of extract of African Mistletoe: Agelanthus Dodoneifolius Polh and Wiens in Rats 

  BUILDER, M. I.; JOSEPH, S.O.; OLUGBEMI, T. O.; AKANDE, T. (NIGERIAN BIOMEDICAL SCIENCE JOURNAL (NBSJ) Vol. 17 No. 1, 2020)

  Agelathus dodoneifolius (AD) which is also known as African mistletoe is widely used to treat different diseases such as circulatory and respiratory diseases, malaria, diabetes, hypertension and sterility. The sub-acute ...
• The Pharmacological Evaluation of Cold Water Stem-Bark Extract of Erythrophleum suaveolens on Gastrointestinal Muscle of Guinea-Pig (Cavia porcellus) Ileum 

  IDYU, I. I.; OLAOYE, T. O.; SOKOMBA, E. N.; IDYU, V. C.; RAMYIL, M. S.; OGBOLE, E. A.; BUILDERS, Modupe I.; OGUNDEKO, T. O. (INTERNATIONAL JOURNAL OF SCIENCE AND RESEARCH (IJSR) Vol. 3 No. 5, 2014-05)

  The effect of cold water crude extract of stem-bark of Erythrophleum suaveolens on the activity of an isolated guinea-pig Ileum was studied. Reference drugs (Acetylcholine, Histamine, Barium Chloride, Atropine, Promethazine, ...
• The Perception of Healthcare Providers on the Quality of Locally Made Drugs and Imported Drugs 

  BUILDERS, Modupe I.; BUILDERS, Philip F.; ILIYA, Linda (JOURNAL OF DRUGS AND PHARMACEUTICAL SCIENCE (JDPS) Vol. 3 No. 1, 2019-04)

  Locally made drugs are an important policy way of reducing out-of-pocket expenditure on medicines. Therefore, negative perceptions of their quality affect utilization and raise issues of confidence and trust in medicines ...
• A Survey of Wound Care Practices by Nurses in a Clinical Setting 

  BUILDERS, Modupe I.; JOSEPH, Simeon Oyepata; BASSI, Peter Usman (INTERNATIONAL JOURNAL OF HEALTHCARE AND MEDICAL SCIENCES (IJHMS) Vol. 6 No. 5, 2020)

  Background: Nurse practitioners play a vital role in wound care and management because of the prevalence of wounds in the community and hospital setting. Aims and objectives: The purpose was to identify current knowledge ...
• Sub-Acute Toxicity Study of Ethanol Leaf Extract of Terminalia Chebula on Brain, Stomach and Spleen of Wister Rats 

  JOSEPH, Oyepata Simeon; BUILDERS, Modupe I.; ISINKAYE, Deborah R.; SEBASTINE, Aliyu Zubairu; MUSA, Tabitha; OYEPATA, J. Philip; JOSEPH, Opeyemi Tosin; WAZIS, Chama (AMERICAN JOURNAL OF BIOMEDICAL SCIENCE & RESEARCH (AJBSR) Vol. 3 No. 3, 2019)

  Introduction/Aim: The incidences of medicinal plant toxicity in the society are becoming serious in the society. There is the need for scientist to determine the toxicity profile of most is therefore very important. ...
• Sub-Acute Toxicity Study of Ethanol Leaf Extract of Ocimum Canum on the Kidney of Wistar Rats 

  JOSEPH, O. S.; BUILDERS, Modupe I.; JOSEPH, O. T.; SABASTINE, A. Z.; MUSA, T. L.; OYEPATA, P. J. (AFRICAN JOURNAL OF PHARMACEUTICAL RESEARCH & DEVELOPMENT (AJPRD) Vol. 11 No.1, 2019)

  The use of plant in treatment of human diseases is as old as man. Medicinal plants are often consumed locally without a graded dose or expected duration of use. This can precipitate unexpected side effects on the tissue, ...
• Sub-Acute Toxicity Study of Ethanol Leaf Extract of Ocimum Canum on Brain, Lungs, Stomach and Spleen of Wister Rats 

  JOSEPH, O. S.; BUILDERS, Modupe I.; JOSEPH, O. T.; SABASTINE, A. Z.; MUSA, T. L.; OYEPATA, P. J. (AFRICAN JOURNAL OF PHARMACEUTICAL RESEARCH & DEVELOPMENT (AJPRD) Vol. 11 No.1, 2019)

  All substances have the potential to be toxic if given to humans and other living organisms in certain conditions and at certain doses or levels. The toxic and adverse effect of traditional medicines may persist long and ...
• Sub-Acute Toxicity Study of Ethanol Leaf Extract of Ocimum Canum on Liver of Wister Rats 

  JOSEPH, O. S.; BUILDERS, Modupe I.; JOSEPH, O. T.; ZUBAIRU, S. A.; MUSA, T.; OYEPATA, P. J. (INTERNATIONAL JOURNAL OF RESEARCH AND SCIENTIFIC INNOVATION (IJRSI) Vol. 6 No. 5, 2019-05)

  Background/Aim: The liver plays an extremely important role in the body. It ensures the removal of toxins and has numerous other functions, including: Fat metabolism, carbohydrate metabolism and protein metabolism. The ...
• Serum Calcium and Phosphorus Levels of HIV/AIDS Positive Patients 

  AKANDE, Tunji; OGUNDEKO, Timothy; OYEGBAMI, Yetunde; OBISESAN, Olutuyi; BUILDERS, Modupe I.; ADENIYI, Olusegun (WORLD WIDE JOURNAL OF MULTIDISCIPLINARY RESEARCH AND DEVELOPMENT (WWJMRD) Vol. 2 No. 2, 2016)

  The management of serum calcium and phosphorus related diseases such as tuberculosis, renal, bone etc. has posed lots of challenges to practicing physicians over the years. HIV/AIDS is another of such that must be accorded ...
• Readability of Drugs and Chemicals Package Inserts Information: A Survey of the Nigerian Market 

  OGUNDEKO, T. O.; OGBOLE, E. A.; BUILDERS, Modupe I.; AKANDE, T.; SOKOMBA, E. N.; TOMA, B.; RAMYIL, M. S. C. (WORLD JOURNAL OF PHARMACEUTICAL AND LIFE SCIENCES (WJPLS) Vol. 4 No. 5, 2018)

  Background: Readability of package inserts (PIs) of drugs, chemicals, reagents, vaccines and similar products is yet to receive adequate attention as little or no concern is accorded to font sizes of leaflet designs ...
• Rational and Irrational Use of Analgesics: A Review 

  BUILDERS, Modupe I. (WORLD JOURNAL OF PHARMACEUTICAL SCIENCES (WJPS) Vol. 4 No. 7, 2016)

  Analgesic misuse is a worldwide problem in developed as well as developing countries. Heavy use of analgesics, particularly over-the-counter (OTC) products, has long been associated with chronic renal failure. Several ...
• Pulmonary Candidiasis and CD4 Count in HIV Positive Patients Seen in Jos, North Central Nigeria 

  PETER, Y. J.; ISA, A. H.; ANZAKU, A. S.; BUILDERS, Modupe I. (AFRICAN JOURNAL OF CLINICAL AND EXPERIMENTAL MICROBIOLOGY (AJCEM) Vol. 7 No. 1, 2016-01)

  Background: Accurate and reliable diagnosis of HIV opportunistic infections plays a central role in effective HIV intervention programmes. Pulmonary infections are the leading cause of morbidity and mortality in HIV infected ...
• Prescription Patterns of Analgesics in a Community Hospital in Nsukka 

  BUILDERS, Modupe I.; OKONTA, J. M.; AGUWA, C. N. (JOURNAL OF PHARMACUETICAL SCIENCE AND RESEARCH (JPSR) Vol. 3 No. 12, 2011)

  Analgesics are one of the most prescribed groups of drugs. Faulty prescription patterns in analgesics often results in aggravated side effects and drug interactions leading to serious adverse drug reactions. In this study ...
• Prescription Pattern of Antimalarial Drugs in a Teaching Hospital in Nigeria 

  BUILDERS, Modupe I.; DEGGE, Hannah; PETER, Jonah Y.; OGBOLE, Emmanuel (BRITISH BIOMEDICAL BULLETIN (BBB) Vol. 2 No. 1, 2014)

  Introduction: As a response to the anti-malarial drug resistance situation, the World Health Organisation (WHO) recommends that treatment policies for falciparum malaria in all countries experiencing resistance to monotherapies ...
• Preparation and Evaluation of Mucinated Sodium Alginate Microparticles for Oral Delivery of Insulin 

  BUILDERS, Philip F.; KUNLE, Olobayo O.; OKPAKU, Larry C.; BUILDERS, Modupe I.; ATTAMA, Anthony A.; ADIKWU, Michael U. (EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (EJPB) Vol. 70, 2008)

  Effective oral insulin delivery remains a challenge to the pharmaceutical industry. In this study, insulinloaded microparticles for oral delivery were prepared with mucin and sodium alginate combined at different ratios ...

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