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Research Articles: Recent submissions

Now showing items 61-80 of 162

Superior Effectiveness of Zidovudine Compared With Tenofovir When Combined With Nevirapine-based Antiretroviral Therapy in a Large Nigerian Cohort

Okonkwo, Prosper (Clinical Infectious Diseases, 2015)

Despite sparse efficacy data, tenofovir–emtricitabine or tenofovir–lamivudine plus nevirapine is used in many resource-constrained settings. Methods. This retrospective cohort study included patients initiating ...
Tuberculosis Incidence and Risk Factors Among Human Immunodeficiency Virus (HIV)-Infected Adults Receiving Antiretroviral Therapy in a Large HIV Program in Nigeria

Okonkwo, Prosper (MAJOR ARTICLE, 2015)

Despite the benefits of antiretroviral therapy (ART), tuberculosis (TB) is the leading cause of mortality among human immunodeficiency virus (HIV)-infected persons in Africa. Nigeria bears the highest TB burden in Africa ...
High Rates of Unplanned Care Interruption: Implications for Program Response

Okonkwo, Prosper (Health Care: Current Reviews, 2015)

Unplanned care interruption (UCI) is an important challenge for HIV programs in resource- limited settings (RLS). More than 1 in 3 patients will interrupt care after starting antiretroviral therapy (ART), predisposing ...
High rates of unplanned interruptions from HIV care early after antiretroviral therapy initiation in Nigeria

Okonkwo, Prosper (BMC Infectious Diseases, 2015)

Unplanned care interruption (UCI) challenges effective HIV treatment. We determined the frequency and risk factors for UCI in Nigeria. Methods: We conducted a retrospective-cohort study of adults initiating antiretroviral ...
Incidence and predictors of adverse drug events in an African cohort of HIV-infected adults treated with efavirenz

Okonkwo, Prosper (2015)

Introduction Adverse drug reactions associated with efavirenz (EFV) therapy are poorly described beyond the first year of treatment. We aimed to describe the incidence and predictors of EFV-related adverse drug reactions ...
High Rate of HIV- Positives in a Surgery Focused Medical Outreach in Jos Nigeria: Lessons from a Provider Initiated HIV Counseling and Testing

Okonkwo, Prosper (SCIENCE PUBLISHING GROUP, 2015)

Background: Despite the multisectoral response to HIV epidemic and the promotion of combination prevention with HIV Counseling and Testing (HCT) as an entry into Treatment, Care and Support, coverage has remained low and ...
Provider Initiated HIV Testing During Antenatal Care and Labour – Knowledge and Acceptability of Patients in a Nigeria Teaching Hospital

Okonkwo, Prosper (European Journal of Preventive Medicine, 2015)

Aim: This study aimed at accessing the knowledge and acceptance of women receiving Antenatal care (ANC) at the Jos University Teaching Hospital (JUTH) to the concept of Provider Initiated HIV Testing and Counselling (PITC) ...
Community based approach to achieving Universal Access to HIV Testing and Counseling

Okonkwo, Prosper (South American Journal of Public Health, 2015)

Introduction: Achieving universal access to HIV services requires a mixture of strategies to increase opportunities for people to know their HIV status. APIN in conjunction with civil society organization and with funding ...
Mother-to-child transmission outcomes of HIV-exposed infants followed up in Jos North-central Nigeria

Okonkwo, Prosper (2015)

Objective: Since 2010, Nigeria adopted World Health Organization (WHO) ‘Option B’ which required administration of triple antiretroviral prophylaxis or treatment (ART) to all HIV-infected pregnant women. We studied the ...
Loss to Follow-up within the Prevention of Mother-to-Child Transmission Care Cascade in a Large ART Program in Nigeria

Okonkwo, Prosper (2015)

Background—The 2013 WHO guidelines incorporated simplified and more effective antiretroviral regimens for the purposes of preventing mother-to-child transmission of HIV. With ideal implementation of these recommendations, ...
Dyslipidemia in ART-Naive HIV-Infected Persons in Nigeria—Implications for Care

Okonkwo, Prosper (Journal of the International Association of Providers of AIDS Care, 2014)

This study aimed to describe the prevalence and pattern of lipid abnormalities among antiretroviral therapy (ART)- naive HIV patients, understand if there is any relationship to virologic and immunologic status, and discuss ...
Predictors of Mortality in a Clinic Cohort of HIV-1 Infected Children Initiated on Antiretroviral Therapy in Jos, Nigeria

Okonkwo, Prosper (HHS Public Access, 2014)

Background: Mortality among human immunodeficiency virus-1 (HIV-1) infected children initiated on antiretroviral therapy (ART) though on a decline still remains high in resource-limited countries (RLC). Identifying baseline ...
HIV prevalence and associated risk factors among rural pregnant women in North Central Nigeria

Okonkwo, Prosper (American Journal of Health Research, 2015-01-29)

To determine the prevalence of HIV infection and associated risk factors among rural pregnant women in Plateau state, Nigeria. Study Design: The study involved a cross-sectional study of pregnant rural women in antenatal ...
Enhancement of Health Research Capacity in Nigeria through North-South and In-Country Partnerships

Okonkwo, Prosper (HSS PUBLIC ACCESS, 2014-08)

Research productivity in Sub-Saharan Africa has the potential to affect teaching, student quality, faculty career development, and translational country-relevant research as it has in developed countries. Nigeria is the ...
Nonadherence to first‑line antiretroviral therapy among human immunodeficiency virus‑1 infected children at the Jos University Teaching Hospital, Jos, Nigeria

Okonkwo, Prosper (2014)

Background: Nonadherence to antiretroviral therapy (ART) may encourage the development of resistance to antiretroviral drugs (ARVs). Poor adherence is known to be associated with ART failure which could compromise the ...
Human immunodeficiency virus and Hepatitis C virus co-infection in children in Jos, Nigeria

Okonkwo, Prosper (OPEN SCIENCE, 2014-05)

Background: Human Immunodeficiency Virus (HIV) and Hepatitis C virus (HCV) share similar modes of transmission and hence co-exist in the same host at significantly high rates. The effect of HIV infection on progression ...
Sero-negative Antibody Status in HIV-Infected Children Initiated on Early Anti-Retroviral Therapy in Jos, Nigeria

Okonkwo, Prosper (2014)

Aim: To determine the association between the age at initiation of anti-retroviral therapy (ART) and the 18 month antibody status of human immunodeficiency virus (HIV)-infected children in Jos, Nigeria. Study Design: ...
Pattern of adverse drug reaction in HIV-infected children on anti-retroviral therapy in Jos, Nigeria

Okonkwo, Prosper (2014)

Background: With the recommendation of highly active anti-retroviral therapy (HAART) as the standard of care for children infected with HIV, their quality of life has improved dramatically. However anti-retroviral (ARV) ...
Zidovudine-Induced Anaemia in Human Immunodeficiency Virus Infected Children on Highly Active Anti-Retroviral Therapy in Jos, Nigeria

Okonkwo, Prosper (Journal of Advances in Medical and Pharmaceutical Sciences, 2014)

Aims: To determine the incidence and severity of zidovudine-induced anaemia in HIVinfected children initiated on anti-retroviral therapy in Jos, Nigeria. Study Design: This was an observational cohort study.Place and ...
Prevalence and Laboratory Profile of Hepatitis B Virus Co-infected Nigerian Children with Human Immunodeficiency Virus

Okonkwo, Prosper (International Journal of TROPICAL DISEASE & Health, 2014)

Aims: To determine the prevalence of HBV co-infection in HIV-infected children and compare the baseline laboratory profile of mono-infected and co-infected patients. Study Design: This was a retrospective cohort study. Place ...

Now showing items 61-80 of 162

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